姓名：姜丹莉
邮箱：hy0322007@hainmc.edu.cn
教育经历：
2005年9月-2009年6月，南昌大学，生命科学学院，学士
2009年9月-2012年6月，汕头大学，海洋生物研究所，硕士
2012年9月-2017年6月，浙江大学，动物科学学院，博士
工作经历：
2017年9月-2018年7月，中山大学，生命科学学院，博士后
2018年8月-2021年8月，美国匹兹堡大学，医学院，博士后
研究方向：
人类疾病相关的post-GWAS研究
细胞衰老分子机制
研究内容：
1. 急性淋巴细胞白血病相关位点CDKN2A/B的功能性单核苷酸多肽性(fSNP)的调控机制研究
2. 克隆造血功能性单核苷酸多肽性(fSNP)的筛选及调控机制研究
Name: Danli Jiang
Email: hy0322007@hainmc.edu.cn
Education background:
2005/9-2009/6, Nanchang University, College of Life Science, Bachelor
2009/9-2012/6, Shantou University, Marine Biology Institute, Master
2012/9-2017/6, Zhejiang University, College of Animal Science, PhD
Work experience:
2017/9-2018/7，Sun Yat-sen University, College of Life Science, Post-doc
2018/8-2021/8，Pittsburgh University, Medical College, Post-doc
Research Area:
post-GWAS analysis on human disease;
Molecular mechanisms of cellular senescence
Research Interests:
1. Regulatory mechanisms of functional single nucleotide polymorphisms (fSNP) on CDKN2A/B loci associated with acute lymphoblastic leukemia；
2. Identification and characterization of functional single nucleotide polymorphisms (fSNP) associated with clonal hematopoiesis
Selected publications:
1. Danli Jiang, Wei Sun, Ting Wu, Meijuan Zou, Sathish Babu Vasamsetti, Xiaoyu Zhang, Yihan Zhao, Sina Tavakoli, Partha Dutta, Jonathan Florentin, Stephen Y. Chan, Di Wu, Jing Cui, Toren Finkel, Gang Li*. “Post-GWAS functional analysis of the CDKN2A/B locus identifies CUX1 as a regulator of p16INK4a expression and cellular senescence.” Nature Aging, 2022, J doi. 10.1038/s43587-022-00177-0.
2. Ting Wu, Danli Jiang, Meijuan Zou, Wei Sun, Di Wu, Jing Cui, Ian Huntress, Xinxia Peng, Gang Li*. Coupling high throughput mapping with proteomics analysis delineates cis-regulatory elements at high resolution. Nucleic Acids Research, 2021, 50(1), e5-e5.
3. Meijuan Zou, Danli Jiang, Ting Wu, Xiaoyu Zhang, Yihan Zhao, Di Wu, Wei Sun, Jing Cui, Larry Moreland, Gang Li*. "Post-GWAS functional studies reveal an RA-associated CD40 induced NF-kB signal transduction and transcriptional regulation network targeted by class II HDAC inhibitors." Human molecular genetics, 2021, 30(9): 823-835.
4. Yihan Zhao, Di Wu, Danli Jiang, Xiaoyu Zhang, Ting Wu, Jing Cui, Min Qian, Jean Zhao, Steffi Oesterreich, Wei Sun, Toren Finkel, Gang Li*. "A sequential methodology for the rapid identification and characterization of breast cancer-associated functional SNPs." Nature communications, 2020, 11(1): 1-11.
5. Meijuan Zou, Xiaoyu Zhang, Danli Jiang, Yihan Zhao, Ting Wu, Qiaoke Gong, Hang Su, Di Wu, Larry Moreland, Gang Li*. Transcriptional Regulation of CD40 Expression by 4 Ribosomal Proteins via a Functional SNP on a Disease-Associated CD40 Locus. Genes (Basel), 2020,11(12):1526.
