楼张蓉简历
邮箱:louzr@dlut.edu.cn
个人网页:http://faculty.dlut.edu.cn/louzhangrong/zh_CN/index.htm
大连理工大学 生物医学工程学院
博士/硕士招生方向
生物光子学、物理化学、有机化学等相关专业
研究领域:
主要从事荧光探针的设计、合成、机理及其生物医学方面的应用研究。利用仿生理念,化学方法模拟谷胱甘肽过氧化物酶的活性中心,发展一系列荧光探针,结合激光共聚焦显微成像技术监测主导生物体内各种生理病理过程的活性氧的动态变化,为药物的筛选及疾病的诊断提供有效的工具。结合DFT/TDDFT计算,深入探究和理解荧光探针中能量和电子转移等动力学过程的本质规律以及结构和功能特性的关系,为开发更多性能优良的检测试剂提供理论支持。
学术成果:
近几年发表部分论文成果
1. (第一作者,高被引论文) Zhangrong Lou, Peng Li, and Keli Han*. Redox-Responsive Fluorescent Probes with Different Design Strategies. Acc. Chem. Res., 2015, 48(5): 1358-1368. SCI收录, IF:22.384 (22.732), JCR: Q1 (CHEMISTRY, MULTIDISCIPLINARY). 被引次数:354.
2. (第一作者) Zhangrong Lou, Panwang Zhou*. Theoretical exploration in the substituent effect on photophysical properties and excited-state intramolecular proton transfer process of benzo [a]imidazo[5,1,2-cd]indolizines. J. Photoch. Photobio. A, 2022, 422, 113570. IF:4.291 (3.854), JCR: Q2 (CHEMISTRY, PHYSICAL).
3. (通讯作者) Yiying Wang, Tianxin Bai, Peng Song, Zhe Tang, Zhangrong Lou*. New insight into the fluorescence mechanism in a fluorescent probe for detecting Zn2+ and CN- through theoretical calculations. J. Mol. Liq., 2021, 343, 117539. IF:6.165 (5.642), JCR: Q1 (PHYSICS, ATOMIC, MOLECULAR & CHEMICAL).
4. (第一作者) Zhangrong Lou, Jinfeng Zhao*, Peng Song*.Exploring the sensing mechanism in a dual-mode fluorescent probe responding to tryptamine and fluoride ions. Chem. Phys. Lett. 2021, 785, 139142. IF:2.328 (1.999), JCR: Q2 (PHYSICS, ATOMIC, MOLECULAR & CHEMICAL); Q3 (CHEMISTRY, PHYSICAL).
5. (第一作者) Zhangrong Lou, Debin Ji*. Theoretical insights into the excited state processes of a novel fluorescent probe for thiophenol with large Stokes shift. J. Photoch. Photobio. A, 2022,422, 113691. IF:4.291, JCR: Q2 (CHEMISTRY, PHYSICAL).