名称 | 简介 |
研究论文 | Yifan Liu, Han Zhao, Li Li, Baoyin Yang, Yongli Yue, Meng Li, Xiaowei Shi, Bo Zhang, Lei Wang, Chaochao Qi, Yibing Liu, Shuguang Ren, Kai Zhang,* , Juyoung Yoon,* A tyrosinase-activated Pt(II) complex for melanoma photodynamic therapy and fuorescence imaging. Sensors and Actuators: B. Chemical, 2023, 374, 132836. |
研究论文 | Hongyi Yan, Yabo Wang, Yongli Yue, Li Li, Xiaowei Shi, Kai Zhang* and Na Xue**. Isolation, synthesis, identification of new process-related impurities in evocalcet. Journal of Pharmaceutical and Biomedical Analysis, 2022, (214): 114715. |
研究论文 | Meng Li, Na Xue, Xingang Liu, Qiaoyun Wang, Hongyi Yan, Yifan Liu, Lei Wang, Xiaowei Shi, Deying Cao, Zhang Kai* and Yang Zhang*. Discovery of Potent EGFR Inhibitors With 6-Arylureido-4-anilinoquinazoline Deivatives, Frontiers in Pharmacology, 2021, 2021(12): 647591. |
研究论文 | Aoyu Wang, Yuhuan Li, Kai Lv*, Rongmei Gao, Apeng Wang, Haiyan Yan, Xiaoyu Qin, Shijie Xu, Chao Ma, Jiandong Jiang, Zengquan Wei, Kai Zhang*, Mingliang Liu*. Optimization and SAR research at the piperazine and phenyl rings of JNJ4796 as new anti-influenza A virus agents, part 1, European Journal of Medicinal Chemistry, 2021, 2021(222): 113591. |
研究论文 | Ma Xican, HanBing, Wang Aoyu, Lu Yang, Huang Menghao, Chowdhury Kushan*, Gu Jian, Zhang Kai*, Lv Kai. Identification of benzothiazones containing a hexahydropyrrolo[3, 4-c]pyrrol moiety as antitubercular agents against MDR-MTB, RSC Advances, 2020, 2020(10): 14410-14414. |
研究论文 | Yang Zhao, Gu Jian-Min, Ma Qiu-Ya, Xue Na, Shi Xiao-Wei, Wang Lei, Zhang Kai*, Wang Ya-Bo, Cao De-Ying, Guo Ran, Xing Rui-Juan, Design, synthesis and antitumor activity of aromatic urea-quinazolines, Future Medicinal Chemistry, 2019, 11(21): 2821-2830. |
研究论文 | Shi Xiaowei, Shang Weiding, Wang Shuang, Xue Na, Hao Yanxia, Wang Yabo, Sun Mengmeng, Du Yumin, Cao Deying, Zhang Kai*, Shi Qingwen*. Simultaneous quantification of naproxcinod and its active metabolite naproxen in rat plasma using LC–MS/MS: Application to a pharmacokinetic study. Journal of Chromatography B, 2015, (978-979): 157-162. |
研究论文 | Shi Xiaowei, Zhang Kai *, Xue Na, Su Linfei, Ma Gaixia, Qi Jinlong, Wu Yibing, Wang Qiao, Shi Qingwen*. Differentiation of genuine Inula britannica L. and substitute specimens based on the determination of 15 components using LC-MS/MS and principal components analysis. Food Chemistry, 2013, 141(4): 4019–4025. |
研究论文 | Zhang Kai, Li Yong, Ni Zhiyu, Zhang Manli. Wang Yufang, Shi Qingwen*, Huo changhong, Sauriol Franaoise, Kiyota Hiromasa*, Gu Yucheng, Dong Mei*. New 6/8/6-Taxanes Isolated from the Heartwood of Taxus cuspidate. Helvetica Chimica Acta, 2012, 95: 1566-1572. |
研究论文 | Zhang Kai, Xue Na, Shi Xiaowei, Liu Weina, Meng Jing, Du Yumin*. A validated chiral liquid chromatographic method for the enantiomeric separation of safinamide mesilate, a new anti-Parkinson drug. Journal of Pharmaceutical and Biomedical Analysis, 2011, 55: 220–224. |
研究论文 | Zhang Kai, Xue Na, Yuan Zhifang, Li Lin, Shi Xiaowei, Cao Liang, Du Yumin*. Separation of the Two Enantiomers of Naproxcinod by Chiral Normal-Phase Liquid Chromatography. Journal of Chromatographic Science, 2011, 49(4): 272-275. |
专利 | 一种维格列汀的制备方法,ZL201710202219.3,第一发明人,已授权。 |
专利 | R-氨磺必利药用盐、制备方法、晶型及其用途,CN 106995397 B,第一发明人,已授权并完成转让。 |
专利 | 苯基脲偶联喹唑啉类化合物的制备方法、药物组合及药物用途,CN 103382182 A,第一发明人,已授权 |
专利 | 一氧化氮供体型非甾体抗炎药β-环糊精或其衍生物包合物及其制备方法和用途,CN 103599547A,第一发明人,已授权。 |
专利 | 张 恺,曹德英,薛 娜,石晓伟,吕凯,芳甲酰脲偶联喹唑啉类化合物及其制备方法、药物组合物及药物用途,已授权,授权日期:2018,09,04,中国,CN 105753793 B,第一发明人,已授权。 |
获奖 | 2017年获得河北省科技进步奖三等奖,第1名。2017JB3010-2. |